Antibiotic Resistance
Antibiotics
Antimicrobial Agent
Antimicrobial Drug Resistance
Antimicrobial Susceptibility Testing (AST)
Bacillus
Bacteria
Bioburden
CFU
Chromogenic media
CLSI
Coccus
Conjugation
Endospore
Enteric Bacteria
EUCAST
Flagellum
Fungi
Gram Stain
Membrane filtration
MIC
Microbiology
Microorganism
Morphology
OPKA
Pathogen
Penicillins
Plasmid
SBA
Spirillum
Spirochaete
SRID – Single Radial Immunodiffusion
Sterility test
Vaccine
Vibrio
Virus
Definition of OPKA
OPKA - Opsonophagocytic Killing Assay.
An assay used to measure the functional capacity of vaccine-candidate raised antibodies. The assay aids in selecting promising vaccines by demonstrating whether the vaccine induced antibodies drive efficient complement deposition and subsequent opsonophagocytic killing.
OPKA makes it possible to reproducibly estimate the phagocytic titre of sera from vaccinated and un-vaccinated individuals.
The assay is used commonly to assess pneumococcal vaccine immunogenicity.