Ames

Antibiotic Resistance

Antibiotics

Antimicrobial Agent

Antimicrobial Drug Resistance

Antimicrobial Susceptibility Testing (AST)

Bacillus

Bacteria

Bioburden

CFU

Chromogenic media

CLSI

Coccus

Conjugation

Endospore

Enteric Bacteria

EUCAST

Flagellum

Fungi

Gram Stain

Membrane filtration

MIC

Microbiology

Microorganism

Morphology

OPKA

Pathogen

Penicillins

Plasmid

SBA

Spirillum

Spirochaete

SRID – Single Radial Immunodiffusion

Sterility test

Vaccine

Vibrio

Virus

Definition of OPKA

OPKA - Opsonophagocytic Killing Assay.

An assay used to measure the functional capacity of vaccine-candidate raised antibodies. The assay aids in selecting promising vaccines by demonstrating whether the vaccine induced antibodies drive efficient complement deposition and subsequent opsonophagocytic killing.

OPKA makes it possible to reproducibly estimate the phagocytic titre of sera from vaccinated and un-vaccinated individuals.

The assay is used commonly to assess pneumococcal vaccine immunogenicity.